Blar i forfatter "Hammerum, Anette M."

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    • Cross-border spread of blaNDM-1- and blaOXA-48-positive Klebsiella pneumoniae: a European collaborative analysis of whole genome sequencing and epidemiological data, 2014 to 2019 

      Ludden, Catherine; Lötsch, Felix; Alm, Erik; Kumar, Narender; Johansson, Karin; Albiger, Barbara; Huang, Te-Din; Denis, Olivier; Hammerum, Anette M.; Hasman, Henrik; Jalava, Jari; Räisänen, Kati; Dortet, Laurent; Jousset, Agnès B.; Gatermann, Sören; Haller, Sebastian; Cormican, Martin; Brennan, Wendy; Grosso, Maria Del; Monaco, Monica; Schouls, Leo; Samuelsen, Ørjan; Pirš, Mateja; Cerar, Tjaša; Oteo-Iglesias, Jésus; Pérez-Vázquez, Maria; Sjöström, Karin; Edquist, Petra; Hopkins, Katie L.; Struelens, Marc J.; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-21)
      An alert regarding an outbreak of carbapenem-resistant <i>Klebsiella pneumoniae</i> carrying <i>bla</i> <sub>NDM-1</sub> and <i>bla</i> <sub>OXA-48</sub> carbapenemase-encoding genes was sent by Germany to European Union (EU)/European Economic Area (EEA) countries in October 2019. Since only limited whole genome sequencing (WGS) data on <i>bla</i> <sub>NDM-1-</sub> and <i>bla</i> <sub>OXA-48</sub>-positive ...

    • Dissemination and Characteristics of a Novel Plasmid-Encoded Carbapenem-Hydrolyzing Class D β-Lactamase, OXA-436, Found in Isolates from Four Patients Involving Six Different Hospitals in Denmark. 

      Samuelsen, Ørjan; Hansen, Frank; Aasnæs, Bettina; Hasman, Henrik; Lund, Bjarte Aarmo; Leiros, Hanna-Kirsti S.; Lilje, Berit; Janice, Jessin; Jakobsen, Lotte; Littauer, Pia; Søes, Lillian M; Holzknecht, Barbara J.; Andersen, Leif P; Stegger, Marc; Andersen, Paal S.; Hammerum, Anette M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-23)
      The diversity of OXA-48-like carbapenemases are continually expanding. In this study, we describe the dissemination and characteristics of a novel class D carbapenemase (CHDL) named OXA-436. In total, six OXA-436-producing Enterobacteriaceae isolates including Enterobacter asburiae (n=3), Citrobacter freundii (n=2) and Klebsiella pneumoniae (n=1) were identified in four patients in the period between ...

    • Escherichia coli Sequence Type 410 Is Causing New International High-Risk Clones 

      Roer, Louise; Overballe-Petersen, Søren; Hansen, Frank; Schønning, Kristian; Wang, Mikala; Røder, Bent L; Hansen, , Dennis S; Justesen, Ulrik S; Andersen, Leif P; Fulgsang-Damgaard, David; Hopkins, Katie L; Woodford, Neil; Falgenhauer, Linda; Chakraborty, Trinad; Samuelsen, Ørjan; Sjöström, Karin; Johannesen, Thor B; Ng, Kim; Nielsen, Jens; Ethelberg, Steen; Stegger, Marc; Hammerum, Anette M.; Hasman, Henrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-18)
      <i>Escherichia coli</i> sequence type 410 (ST410) has been reported worldwide as an extraintestinal pathogen associated with resistance to fluoroquinolones, third-generation cephalosporins, and carbapenems. In the present study, we investigated national epidemiology of ST410 <i>E. coli</i> isolates from Danish patients. Furthermore, <i>E. coli</i> ST410 was investigated in a global context to provide ...

    • The global dissemination of hospital clones of Enterococcus faecium 

      van Hal, Sebastiaan J.; Willems, Rob J.L.; Gouliouris, Theodore; Ballard, Susan A.; Coque, Teresa M.; Hammerum, Anette M.; Hegstad, Kristin; Westh, Henrik; Howden, Benjamin P.; Malhotra-Kumar, Surbhi; Werner, Guido; Yanagihara, Katsunori; Earl, Ashlee M.; Raven, Katherine E.; Corander, Jukka; Bowden, Rory (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-30)
      <i>Background</i> - The hospital-adapted A1 group of <i>Enterococcus faecium</i> remains an organism of significant concern in the context of drug-resistant hospital-associated infections. How this pathogen evolves and disseminates remains poorly understood.<br><br> <i>Methods</i> - A large, globally representative collection of short-read genomic data from the hospital-associated A1 group of ...

    • Update on prevalence and mechanisms of resistance to linezolid, tigecycline and daptomycin in enterococci in Europe: towards a common nomenclature 

      Bender, Jennifer; Cattoir, Vincent; Hegstad, Kristin; Sadowy, Eva; Coque, Teresa M.; Westh, Henrik; Hammerum, Anette M.; Schaffer, Kirsten; Burns, Karen; Murchan, Stephen; Novais, Carla; Freitas, Ana R.; Peixe, Luísa; Del Grosso, Maria; Pantosti, Annalisa; Werner, Guido (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-02)
      Vancomycin-resistant enterococci (VRE) are important nosocomial pathogens. Invasive VRE infections are difficult to treat since common therapeutic options including ampicillin and glycopeptides often fail. In vitro, most VRE remain susceptible to last-resort antibiotics such as linezolid, tigecycline and daptomycin. However, neither tigecycline nor linezolid act in a bactericidal manner, and ...